{"id":13317,"date":"2026-02-18T10:36:37","date_gmt":"2026-02-18T06:36:37","guid":{"rendered":"https:\/\/medscriptum.org\/?p=13317"},"modified":"2026-02-18T10:42:18","modified_gmt":"2026-02-18T06:42:18","slug":"scientists-have-found-a-new-way-to-treat-severe-depression","status":"publish","type":"post","link":"https:\/\/medscriptum.org\/en\/scientists-have-found-a-new-way-to-treat-severe-depression\/","title":{"rendered":"Scientists have found a new way to treat severe depression"},"content":{"rendered":"<p data-path-to-node=\"3\"><span class=\"\">According to scientists,<\/span><span class=\"\"> the psychedelic substance <\/span><b class=\"\" data-path-to-node=\"3\" data-index-in-node=\"51\">DMT (dimethyltryptamine)<\/b><span class=\"\">,<\/span><span class=\"\"> when combined with psychotherapy,<\/span><span class=\"\"> can provide rapid and long-lasting improvement in patients with severe forms of depression.<\/span><span class=\"\"> Clinical trials have shown that even a <\/span><b class=\"\" data-path-to-node=\"3\" data-index-in-node=\"242\">single dose<\/b><span class=\"\"> of the drug significantly reduced symptoms,<\/span><span class=\"\"> with results persisting for up to six months in some patients.<\/span><\/p>\n<p data-path-to-node=\"4\"><span class=\"\">The drug helps the brain break down established,<\/span><span class=\"\"> unhealthy thought patterns,<\/span><span class=\"\"> allowing the patient to discover new,<\/span><span class=\"\"> positive perspectives through psychotherapy.<\/span><span class=\"\"> The study involved individuals with <\/span><b class=\"\" data-path-to-node=\"4\" data-index-in-node=\"196\">&#8220;treatment-resistant depression&#8221;<\/b><span class=\"\"> who no longer responded to standard antidepressants.<\/span><span class=\"\"> Results showed that those who received DMT experienced a sharp decline in depression levels compared to the placebo group.<\/span><\/p>\n<p data-path-to-node=\"5\"><span class=\"\">DMT is the active ingredient in the South American ritual drink,<\/span> <b class=\"\" data-path-to-node=\"5\" data-index-in-node=\"65\">Ayahuasca<\/b><span class=\"\">,<\/span><span class=\"\"> and it stands out from other similar psychedelics due to several key advantages for medical practice.<\/span><span class=\"\"> The primary benefit of this substance is its <\/span><b class=\"\" data-path-to-node=\"5\" data-index-in-node=\"223\">short duration of action<\/b><span class=\"\">:<\/span><span class=\"\"> the effect lasts approximately 25 minutes.<\/span><span class=\"\"> This factor is much more convenient for clinical management,<\/span><span class=\"\"> unlike other substances whose effects can last for several hours.<\/span><\/p>\n<p data-path-to-node=\"6\"><span class=\"\">However,<\/span><span class=\"\"> despite the short duration,<\/span><span class=\"\"> DMT is characterized by <\/span><b class=\"\" data-path-to-node=\"6\" data-index-in-node=\"61\">extraordinary intensity<\/b><span class=\"\">,<\/span><span class=\"\"> which requires significant emotional effort from the patient and constant,<\/span><span class=\"\"> highly qualified psychological support from specialists.<\/span><span class=\"\"> Approximately 100 million people worldwide suffer from depression that does not respond to treatment.<\/span><span class=\"\"> Scientists hope that psychedelic therapy will become a viable solution for them.<\/span><\/p>\n<p data-path-to-node=\"6\"><a href=\"https:\/\/www.nature.com\/articles\/s41591-025-04154-z\" target=\"_blank\" rel=\"noopener\">Nature<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>According to scientists, the psychedelic substance DMT (dimethyltryptamine), when combined with psychotherapy, can provide rapid and long-lasting improvement in patients with severe forms of depression. Clinical trials have shown that even a single dose of the drug significantly reduced symptoms, with results persisting for up to six months in some patients. The drug helps the [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":13316,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1631,1594,1645,1587,1657],"tags":[3819,4444],"class_list":["post-13317","post","type-post","status-publish","format-standard","has-post-thumbnail","category-neurology","category-news","category-psychiatry","category-research","category-science","tag-depression","tag-dmt"],"acf":[],"_links":{"self":[{"href":"https:\/\/medscriptum.org\/en\/wp-json\/wp\/v2\/posts\/13317","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medscriptum.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medscriptum.org\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medscriptum.org\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/medscriptum.org\/en\/wp-json\/wp\/v2\/comments?post=13317"}],"version-history":[{"count":2,"href":"https:\/\/medscriptum.org\/en\/wp-json\/wp\/v2\/posts\/13317\/revisions"}],"predecessor-version":[{"id":13321,"href":"https:\/\/medscriptum.org\/en\/wp-json\/wp\/v2\/posts\/13317\/revisions\/13321"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medscriptum.org\/en\/wp-json\/wp\/v2\/media\/13316"}],"wp:attachment":[{"href":"https:\/\/medscriptum.org\/en\/wp-json\/wp\/v2\/media?parent=13317"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medscriptum.org\/en\/wp-json\/wp\/v2\/categories?post=13317"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medscriptum.org\/en\/wp-json\/wp\/v2\/tags?post=13317"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}