{"id":15644,"date":"2026-03-30T15:46:24","date_gmt":"2026-03-30T11:46:24","guid":{"rendered":"https:\/\/medscriptum.org\/?p=15644"},"modified":"2026-03-30T16:27:07","modified_gmt":"2026-03-30T12:27:07","slug":"ai-based-clinical-trials-may-be-flawed-new-study","status":"publish","type":"post","link":"https:\/\/medscriptum.org\/en\/ai-based-clinical-trials-may-be-flawed-new-study\/","title":{"rendered":"AI-based clinical trials may be flawed: New study"},"content":{"rendered":"<p data-path-to-node=\"3\"><span class=\"\">Scientists at the <\/span><b class=\"\" data-path-to-node=\"3\" data-index-in-node=\"18\">University of York<\/b><span class=\"\"> have discovered a significant flaw in Artificial Intelligence models,<\/span><span class=\"\"> challenging the widespread belief that machine algorithms operate similarly to the human brain.<\/span><span class=\"\"> Although artificial neural networks have long been considered the best models for the human cognitive system,<\/span><span class=\"\"> the new research shows that their internal strategies do not fully align with the principles of primate brain function.<\/span><\/p>\n<p data-path-to-node=\"4\"><span class=\"\">AI models are increasingly being used in clinical trials to study human behavior,<\/span><span class=\"\"> including treatments for <\/span><b class=\"\" data-path-to-node=\"4\" data-index-in-node=\"107\">autism<\/b><span class=\"\"> and <\/span><b class=\"\" data-path-to-node=\"4\" data-index-in-node=\"118\">Post-Traumatic Stress Disorder (PTSD)<\/b><span class=\"\">.<\/span><span class=\"\"> If a model perceives the world differently from a human,<\/span><span class=\"\"> its use in experiments could be hazardous.<\/span><\/p>\n<p data-path-to-node=\"5\"><strong>What does the study say?<\/strong><\/p>\n<p data-path-to-node=\"6\"><span class=\"\">Until now,<\/span><span class=\"\"> scientists tested AI only one-dimensionally,<\/span><span class=\"\"> observing how effectively a program could predict human brain reactions.<\/span><span class=\"\"> Researchers at the University of York,<\/span><span class=\"\"> however,<\/span><span class=\"\"> logically reversed this approach.<\/span><\/p>\n<p data-path-to-node=\"7\"><span class=\"\">Their theory is based on the premise that if AI is truly a digital copy of the human brain,<\/span><span class=\"\"> the connection must be <\/span><b class=\"\" data-path-to-node=\"7\" data-index-in-node=\"115\">bidirectional<\/b><span class=\"\">.<\/span><span class=\"\"> In other words,<\/span><span class=\"\"> by observing our brain activity,<\/span><span class=\"\"> we should be able to precisely determine which operations are being performed within the AI model.<\/span><\/p>\n<p data-path-to-node=\"8\"><span class=\"\">To test this theory,<\/span><span class=\"\"> researchers conducted a large-scale experiment using over 1,<\/span><span class=\"\">600 different types of images,<\/span><span class=\"\"> ranging from real photos of animals to schematic drawings and artistic variations.<\/span><\/p>\n<p data-path-to-node=\"9\"><span class=\"\">The study revealed that while AI can explain the behavior of human neurons relatively well,<\/span><span class=\"\"> the human brain cannot predict AI\u2019s internal computations with the same accuracy.<\/span><span class=\"\"> This suggests that the similarity between them is only superficial,<\/span><span class=\"\"> and the programs operate on entirely different principles.<\/span><\/p>\n<p data-path-to-node=\"10\"><span class=\"\">Ultimately,<\/span><span class=\"\"> the research confirmed that modern AI processes visual information using strategies that nature and human evolution do not utilize at all.<\/span><span class=\"\"> This discovery is critically important; if AI perceives the world differently than we do,<\/span><span class=\"\"> its application in medical research or psychological experiments could lead to <\/span><b class=\"\" data-path-to-node=\"10\" data-index-in-node=\"320\">erroneous conclusions<\/b><span class=\"\">.<\/span><span class=\"\"> Scientists are now working to align these programs more closely with the actual biological principles of brain function.<\/span><\/p>\n<p data-path-to-node=\"11\">Researchers have already developed specialized testing tools to help AI developers improve their models. The goal is to create Artificial Intelligence that is maximally compatible with the human brain. This is particularly vital for modeling <b data-path-to-node=\"11\" data-index-in-node=\"242\">neurotypical brains<\/b>, which serves as the foundation for future medical research.<\/p>\n<p data-path-to-node=\"11\"><a href=\"https:\/\/www.nature.com\/articles\/s42256-026-01204-0\" target=\"_blank\" rel=\"noopener\">Nature<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Scientists at the University of York have discovered a significant flaw in Artificial Intelligence models, challenging the widespread belief that machine algorithms operate similarly to the human brain. Although artificial neural networks have long been considered the best models for the human cognitive system, the new research shows that their internal strategies do not fully [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":15643,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1631,1594,1665,1587,1657,1659],"tags":[1948,4966,3124],"class_list":["post-15644","post","type-post","status-publish","format-standard","has-post-thumbnail","category-neurology","category-news","category-public-health","category-research","category-science","category-technologies","tag-ai","tag-ai-based-clinical-trials","tag-khelovnuri-inteleqti"],"acf":[],"_links":{"self":[{"href":"https:\/\/medscriptum.org\/en\/wp-json\/wp\/v2\/posts\/15644","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medscriptum.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medscriptum.org\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medscriptum.org\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/medscriptum.org\/en\/wp-json\/wp\/v2\/comments?post=15644"}],"version-history":[{"count":1,"href":"https:\/\/medscriptum.org\/en\/wp-json\/wp\/v2\/posts\/15644\/revisions"}],"predecessor-version":[{"id":15647,"href":"https:\/\/medscriptum.org\/en\/wp-json\/wp\/v2\/posts\/15644\/revisions\/15647"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medscriptum.org\/en\/wp-json\/wp\/v2\/media\/15643"}],"wp:attachment":[{"href":"https:\/\/medscriptum.org\/en\/wp-json\/wp\/v2\/media?parent=15644"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medscriptum.org\/en\/wp-json\/wp\/v2\/categories?post=15644"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medscriptum.org\/en\/wp-json\/wp\/v2\/tags?post=15644"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}