{"id":22161,"date":"2026-07-16T10:10:44","date_gmt":"2026-07-16T06:10:44","guid":{"rendered":"https:\/\/medscriptum.org\/?p=22161"},"modified":"2026-07-16T10:13:34","modified_gmt":"2026-07-16T06:13:34","slug":"scientists-have-discovered-a-hormone-that-blocks-the-feeling-of-hunger-in-anorexia","status":"publish","type":"post","link":"https:\/\/medscriptum.org\/en\/scientists-have-discovered-a-hormone-that-blocks-the-feeling-of-hunger-in-anorexia\/","title":{"rendered":"Scientists have discovered a hormone that blocks the feeling of hunger in anorexia"},"content":{"rendered":"<p data-path-to-node=\"3\"><span class=\"\">Anorexia nervosa is a complex and life-threatening disorder that has the highest mortality rate among mental illnesses.<\/span><span class=\"\"> Despite its severity,<\/span><span class=\"\"> there is currently no effective medication for its treatment,<\/span><span class=\"\"> and the risk of relapse after patient monitoring and recovery reaches nearly 40%.<\/span><span class=\"\"> However,<\/span><span class=\"\"> a new study presented at the Federation of European Neuroscience Societies (FENS) 2026 Forum demonstrated that anorexia is not solely a psychiatric problem but has a solid metabolic foundation.<\/span><\/p>\n<p data-path-to-node=\"4\"><span class=\"\">The study,<\/span><span class=\"\"> conducted by French neuroscientists,<\/span><span class=\"\"> revealed a link between the gut and the brain,<\/span><span class=\"\"> in which the hormone LEAP2 plays a key role.<\/span><span class=\"\"> Produced by the liver and intestines,<\/span><span class=\"\"> this hormone counters and suppresses the action of ghrelin,<\/span><span class=\"\"> the body&#8217;s primary hunger-triggering signal.<\/span><span class=\"\"> Researchers discovered that patients in the acute phase of anorexia have 20% higher levels of this hormone in their blood,<\/span><span class=\"\"> which restricts their body&#8217;s ability to perceive natural hunger signals.<\/span><\/p>\n<p data-path-to-node=\"5\"><span class=\"\">Scientists explain that the level of LEAP2 is directly linked to the risk of post-treatment relapse.<\/span><span class=\"\"> Patients who exhibited the highest levels of this hormone upon admission and during subsequent therapy were much more likely to relapse six months after discharge.<\/span><span class=\"\"> This means that by analyzing hormone levels,<\/span><span class=\"\"> doctors will be able to predict in advance which patients require longer and more intensive support.<\/span><\/p>\n<p data-path-to-node=\"6\"><span class=\"\">Parallel tests on mice and humans also showed that LEAP2 influences impulse control,<\/span><span class=\"\"> blood sugar regulation,<\/span><span class=\"\"> and the body&#8217;s unusual metabolic tolerance to starvation.<\/span><span class=\"\"> It is this hormonal imbalance that makes it easier for patients to abstain from food intake for months or even years.<\/span><span class=\"\"> The authors of the study hope that decoding this biological mechanism will lay the groundwork for developing effective medical therapies for anorexia in the future.<\/span><\/p>\n<p data-path-to-node=\"6\"><a href=\"https:\/\/fens2026.abstractserver.com\/program\/#\/details\/presentations\/192\" target=\"_blank\" rel=\"noopener\">FENS2026<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Anorexia nervosa is a complex and life-threatening disorder that has the highest mortality rate among mental illnesses. Despite its severity, there is currently no effective medication for its treatment, and the risk of relapse after patient monitoring and recovery reaches nearly 40%. However, a new study presented at the Federation of European Neuroscience Societies (FENS) [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":22160,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1631,1594,1665,1587,1657],"tags":[6311],"class_list":["post-22161","post","type-post","status-publish","format-standard","has-post-thumbnail","category-neurology","category-news","category-public-health","category-research","category-science","tag-anorexia"],"acf":[],"_links":{"self":[{"href":"https:\/\/medscriptum.org\/en\/wp-json\/wp\/v2\/posts\/22161","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medscriptum.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medscriptum.org\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medscriptum.org\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/medscriptum.org\/en\/wp-json\/wp\/v2\/comments?post=22161"}],"version-history":[{"count":2,"href":"https:\/\/medscriptum.org\/en\/wp-json\/wp\/v2\/posts\/22161\/revisions"}],"predecessor-version":[{"id":22166,"href":"https:\/\/medscriptum.org\/en\/wp-json\/wp\/v2\/posts\/22161\/revisions\/22166"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medscriptum.org\/en\/wp-json\/wp\/v2\/media\/22160"}],"wp:attachment":[{"href":"https:\/\/medscriptum.org\/en\/wp-json\/wp\/v2\/media?parent=22161"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medscriptum.org\/en\/wp-json\/wp\/v2\/categories?post=22161"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medscriptum.org\/en\/wp-json\/wp\/v2\/tags?post=22161"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}