Why Did Experts Feel the Need to Redefine Heart Failure?

A diagnosis of heart failure (HF) has never been established based on a single test alone. Nevertheless, clinical practice continues to be dominated by...

The 2026 ABC Framework for Cardiovascular Disease Prevention

Despite decades of progress, cardiovascular disease (CVD) remains the leading cause of global mortality. The challenge lies not in a lack of knowledge or...

Rethinking the Diagnosis and Management of Acromegaly – Interview with Professor Aart Jan (AJ) van der Lely

There are diseases that do not announce themselves - they accumulate. A change in ring size, a shift in facial features, a persistent headache...

How Epigenetics is Changing the Future of Disease Treatment

The history of treating genetic diseases is a constant endeavor to decipher the biological code of life. While this process was initially quite crude,...

The Unexpected Role of Basophils and Mast Cells in Oncology

For decades, basophils and mast cells were considered exclusive mediators of allergic reactions and hypersensitivity type I responses. In both popular understanding and classical...

The Endocrine Society Clinical Practice Guideline on Central Precocious Puberty

Central Precocious Puberty (CPP) is a condition driven by the premature activation of the hypothalamic-pituitary-gonadal (HPG) axis, manifesting before the age of 8 in...

Phase 3 Trial of First In Vivo CRISPR Therapy for Hereditary Angioedema Achieves Landmark Success

Researchers from Amsterdam University Medical Center (Amsterdam UMC), in collaboration with leading clinical centers across 11 countries, have successfully completed the world’s first Phase...

The Supplement Aisle is Floated with Promises—Here is What Evidence-Based Medicine Actually Demonstrates

Billions of dollars are expended globally each year on dietary supplements. Aggressive marketing campaigns project absolute confidence, their therapeutic claims are all-encompassing, and the...