According to the world’s largest study published in the journal The Lancet, the majority of statin side effects are not actually caused by the medication itself. Researchers analyzed 19 randomized controlled trials involving 124,000 participants and concluded that out of 66 side effects listed on drug labels, only a few are scientifically proven.
Statins are a class of medications primarily used to lower levels of “bad” cholesterol (LDL) in the blood. They block a specific enzyme in the liver responsible for cholesterol production, thereby preventing the buildup of atherosclerotic plaques on blood vessel walls.
These drugs are vital for the prevention of cardiovascular diseases, as they significantly reduce the risk of heart attacks, strokes, and other fatal complications.
What did the study confirm?
In addition to the known risks of muscle pain and diabetes, evidence confirmed only four side effects:
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Changes in liver function tests;
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Minor liver disorders;
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Changes in urine composition;
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Tissue swelling (edema).
Researchers emphasize that even the risk of developing these conditions is very low.
Why is this study important?
The study showed that there is no real link between statins and common complaints such as memory loss, depression, sleep disorders, or nervous system damage. According to scientists, the frequency of these symptoms in statin users is exactly the same as in those who do not take the drug at all. This means that while individuals may experience such issues during treatment, statins are not the underlying cause.
For decades, millions of people have refused to take statins due to misinformation and fear of side effects. Representatives of the British Heart Foundation state that this study is a decisive response to disinformation, which will help reduce premature deaths caused by cardiovascular diseases. Experts are now calling for an urgent revision of drug labels so that patients and doctors can make more informed decisions.
